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Publications

2021 2020 2019

The effectiveness of systemic therapies after surgery for metastatic renal cell carcinoma to the spine: a propensity analysis controlling for sarcopenia, frailty, and nutrition.
Massaad E, Saylor PJ, Hadzipasic M, Kiapour A, Oh K, Schwab JH, Schoenfeld AJ, Shankar GM, Shin JH.J Neurosurg Spine. 2021 Jun 25:1-10. doi: 10.3171/2020.12.SPINE201896
Temporizing Wound VAC Dressing Until Final Negative Margins are Achieved Reduces Myxofibrosarcoma Local Recurrence.
Fourman MS, Ramsey DC, Kleiner J, Daud A, Newman ET, Schwab JH, Chen YL, DeLaney TF, Mullen JT, Raskin KA, Lozano-Calderón SA.Ann Surg Oncol. 2021 Jun 18. doi: 10.1245/s10434-021-10242-4
ASO Visual Abstract: Temporizing Wound VAC Dressing Until Final Negative Margins are Achieved Reduces Myxofibrosarcoma Local Recurrence.
Fourman MS, Ramsey DC, Kleiner J, Daud A, Newman ET, Schwab JH, Chen YL, DeLaney TF, Mullen JT, Raskin KA, Lozano-Calderon S.Ann Surg Oncol. 2021 Jun 11. doi: 10.1245/s10434-021-10302-9
Clinical Utility of Anchored Multiplex Solid Fusion Assay for Diagnosis of Bone and Soft Tissue Tumors.Chebib I, Taylor MS, Nardi V, Rivera MN, Lennerz JK, Cote GM, Choy E, Lozano Calderón SA, Raskin KA, Schwab JH, Mullen JT, Chen YE, Hung YP, Nielsen GP, Deshpande V.Am J Surg Pathol. 2021 Jun 10. doi: 10.1097/PAS.0000000000001745
Wide range of applications for machine-learning prediction models in orthopedic surgical outcome: a systematic review.Ogink PT, Groot OQ, Karhade AV, Bongers MER, Oner FC, Verlaan JJ, Schwab JH.Acta Orthop. 2021 Jun 10:1-6. doi: 10.1080/17453674.2021.1932928
Quality of Life Changes After Surgery for Metastatic Spinal Disease: A Systematic Review and Meta-analysis.
Paulino Pereira NR, Groot OQ, Verlaan JJ, Bongers MER, Twining PK, Kapoor ND, van Dijk CN, Schwab JH, Bramer JAM.Clin Spine Surg. 2021 Jun 9. doi: 10.1097/BSD.0000000000001213
Surface osteosarcoma: Predictors of outcomes.Lee SJ, Lans J, Cook SD, Chebib I, Schwab JH, Raskin KA, Lozano-Calderón S.J Surg Oncol. 2021 May 27. doi: 10.1002/jso.26531
The NIMS Framework: An approach to the evaluation and management of epidural abscesses.
Xiong GX, Crawford AM, Striano B, Lightsey HM 4th, Nelson SB, Schwab JH.Spine J. 2021 May 16:S1529-9430(21)00243-6. doi: 10.1016/j.spinee.2021.05.012
Systematic review of charged-particle therapy for chordomas and sarcomas of the mobile spine and sacrum.
Pennington Z, Ehresman J, Elsamadicy AA, Shin JH, Goodwin CR, Schwab JH, Sciubba DM. Neurosurg Focus. 2021 May

Machine learning driven tools in orthopaedics and spine surgery: Hype or reality? Applications and perception of 31 physician opinions
Lans A, Oosterhoff JHF, Groot OQ, Fourman MS. Seminars in Spine Surgery 2021 doi: 2021.100871
High TIL, HLA, and Immune Checkpoint Expression in Conventional High-Grade and Dedifferentiated Chondrosarcoma and Poor Clinical Course of the Disease.
Nota SPFT, Al-Sukaini A, Patel SS, Sabbatino F, Nielsen GP, Deshpande V, Yearley JH, Ferrone S, Wang X, Schwab JH.Front Oncol. 2021 Apr 12;11:598001. doi: 10.3389/fonc.2021.598001
Spnal metastases 2021: a review of the current state of the art and future directions.
Sciubba DM, Pennington Z, Colman MW, Goodwin CR, Laufer I, Patt JC, Redmond KJ, Saylor P, Shin JH, Schwab JH, Schoenfeld AJ; NASS Spine Oncology Committee.Spine J. 2021 Apr 19:S1529-9430(21)00195-9. doi: 10.1016/j.spinee.2021.04.012. Online ahead of print.PMID: 33887454 Review

Availability and reporting quality of external validations of machine-learning prediction models with orthopedic surgical outcomes: a systematic review.
Groot OQ, Bindels BJJ, Ogink PT, Kapoor ND, Twining PK, Collins AK, Bongers MER, Lans A, Oosterhoff JHF, Karhade AV, Verlaan JJ, Schwab JH.Acta Orthop. 2021 Apr 18:1-9. doi: 10.1080/17453674.2021.1910448. Online ahead of print.PMID: 33870837
Value-based health care in spine: where do we go from here?
Karhade AV, Bono CM, Makhni MC, Schwab JH, Sethi RK, Simpson AK, Feeley TW, Porter ME.Spine J. 2021 Apr 20:S1529-9430(21)00177-7. doi: 10.1016/j.spinee.2021.04.006
Updated external validation of the SORG machine learning algorithms for prediction of ninety-day and one-year mortality after surgery for spinal metastasis
Shah AA, Karhade AV, Park HY, Sheppard WL, Macyszyn LJ, Everson RG, Shamie AN, Park DY, Schwab JH, Hornicek FJ.Spine J. 2021 Mar 31:S1529-9430(21)00163-7. doi:10.1016/j.spinee.2021.03.026
Introduction to the special issue of The Spine Journal on artificial intelligence and machine learning.Karhade AV, Schwab JH.Spine J. 2021 Mar 27:S1529-9430(21)00165-0. doi: 10.1016/j.spinee.2021.03.028. Online ahead of print.PMID: 33785475


Augmented and virtual reality in spine surgery, current applications and future potentials.Ghaednia H, Fourman MS, Lans A, Detels K, Dijkstra H, Lloyd S, Sweeney A, Oosterhoff JHF, Schwab JH.Spine J. 2021 Mar 25:S1529-9430(21)00155-8. doi: 10.1016/j.spinee.2021.03.018.
Prospective comparison of the accuracy of the New England Spinal Metastasis Score (NESMS) to legacy scoring systems in prognosticating outcomes following treatment of spinal metastases.
Schoenfeld AJ, Ferrone ML, Blucher JA, Agaronnik N, Nguyen L, Tobert DG, Balboni TA, Schwab JH, Shin JH, Sciubba DM, Harris MB.Spine J. 2021 Mar 16:S1529-9430(21)00118-2. doi: 10.1016/j.spinee.2021.03.007

Machine learning prediction models in orthopedic surgery: A systematic review in transparent reporting.Groot OQ, Ogink PT, Lans A, Twining PK, Kapoor ND, DiGiovanni W, Bindels BJJ, Bongers MER, Oosterhoff JHF, Karhade AV, Oner FC, Verlaan JJ, Schwab JH.J Orthop Res. 2021 Mar 18. doi: 10.1002/jor.25036
Erratum to: Development and Internal Validation of Machine Learning Algorithms for Preoperative Survival Prediction of Extremity Metastatic Disease.Thio QCBS, Karhade AV, Bindels B, Ogink PT, Bramer JAM, Ferrone ML, Calderón SL, Raskin KA, Schwab JH.Clin Orthop Relat Res. 2021 Apr 1;479(4):862. doi: 10.1097/CORR.0000000000001678.PMID: 33704109 
Prospective study for establishing minimal clinically important differences in patients with surgery for lower extremity metastases.Bongers MER, Groot OQ, Thio QCBS, Bramer JAM, Verlaan JJ, Newman ET, Raskin KA, Lozano-Calderon SA, Schwab JH.Acta Oncol. 2021 Jun;60(6):714-720. doi: 10.1080/0284186X.2021.1890333
Complications and Survivorship of Distal Humeral Allograft Reconstruction After Tumor Resection: Literature Review and Case Series.Kamalapathy P, Shah A, Raskin K, Schwab JH, Lozano-Calderón SA.J Am Acad Orthop Surg Glob Res Rev. 2021 Feb 11;5(2):e20.00256-8. doi: 10.5435/JAAOSGlobal-D-20-00256
Targeting cancer stem cells by disulfiram and copper sensitizes radioresistantchondrosarcoma to radiation.
Wang K, Michelakos T, Wang B, Shang Z, DeLeo AB, Duan Z, Hornicek FJ, Schwab JH, Wang X.Cancer Lett. 2021 May 1;505:37-48. doi: 10.1016/j.canlet.2021.02.002
International external validation of the SORG machine learning algorithms for predicting 90-day and 1-year survival of patients with spine metastases using a Taiwanese cohort.
Yang JJ, Chen CW, Fourman MS, Bongers MER, Karhade AV, Groot OQ, Lin WH, Yen HK, Huang PH, Yang SH, Schwab JH, Hu MH.Spine J. 2021 Feb 2:S1529-9430(21)00060-7. doi: 10.1016/j.spinee.2021.01.027
B7-H3 targeted antibody-based immunotherapy of malignant diseases.
Michelakos T, Kontos F, Barakat O, Maggs L, Schwab JH, Ferrone CR, Ferrone S.Expert Opin Biol Ther. 2021 May;21(5):587-602. doi: 10.1080/14712598.2021.1862791
Defective HLA Class I Expression and Patterns of Lymphocyte Infiltration in Chordoma Tumors.
Patel SS, Nota SP, Sabbatino F, Nielsen GP, Deshpande V, Wang X, Ferrone S, Schwab JH.Clin Orthop Relat Res. 2021 Jun 1;479(6):1373-1382. doi: 10.1097/CORR.0000000000001587
Do Cohabitants Reliably Complete Questionnaires for Patients in a Terminal Cancer Stage when Assessing Quality of Life, Pain, Depression, and Anxiety?Groot OQ, Paulino Pereira NR, Bongers MER, Ogink PT, Newman ET, Verlaan JJ, Raskin KA, Lozano-Calderon SA, Schwab JH.Clin Orthop Relat Res. 2021 Apr 1;479(4):792-801. doi: 10.1097/CORR.0000000000001525.PMID: 33165035
Postoperative adverse events secondary to iatrogenic vascular injury during anterior lumbar spinal surgery.
Groot OQ, Hundersmarck D, Lans A, Bongers MER, Karhade AV, Zhang Y, van Tol FR, Verlaan JJ, Mohebali J, Schwab JH.Spine J. 2021 May;21(5):795-802. doi: 10.1016/j.spinee.2020.10.031
Laminoplasty-an underutilized procedure for cervical spondylotic myelopathy.
Lopez WY, Goh BC, Upadhyaya S, Ziino C, Georgakas PJ, Gupta A, Tobert DG, Fogel HA, Cha TD, Schwab JH, Bono CM, Hershman SH.Spine J. 2021 Apr;21(4):571-577. doi: 10.1016/j.spinee.2020.10.021. Epub 2020 Nov 2.PMID: 33152508
Development of prediction models for clinically meaningful improvement in PROMIS scores after lumbar decompression.
Karhade AV, Fogel HA, Cha TD, Hershman SH, Doorly TP, Kang JD, Bono CM, Harris MB, Schwab JH, Tobert DG.Spine J. 2021 Mar;21(3):397-404. doi: 10.1016/j.spinee.2020.10.026. Epub 2020 Oct 31.PMID: 33130302
B7-H3: An Attractive Target for Antibody-based Immunotherapy.
Kontos F, Michelakos T, Kurokawa T, Sadagopan A, Schwab JH, Ferrone CR, Ferrone S.Clin Cancer Res. 2021 Mar 1;27(5):1227-1235. doi: 10.1158/1078-0432.CCR-20-2584. Epub 2020 Oct 13.PMID: 33051306 Review.
Surgeon-level variance in achieving clinical improvement after lumbar decompression: the importance of adequate risk adjustment.Karhade AV, Sisodia RC, Bono CM, Fogel HA, Hershman SH, Cha TD, Doorly TP, Kang JD, Schwab JH, Tobert DG.Spine J. 2021 Mar;21(3):405-410. doi: 10.1016/j.spinee.2020.10.005
Pleiotropic Mechanisms Drive Endocrine Resistance in the Three-Dimensional Bone Microenvironment.
Dhimolea E, de Matos Simoes R, Kansara D, Weng X, Sharma S, Awate P, Liu Z, Gao D, Mitsiades N, Schwab JH, Chen Y, Jeselsohn R, Culhane AC, Brown M, Georgakoudi I, Mitsiades CS.Cancer Res. 2021 Jan 15;81(2):371-383. doi: 10.1158/0008-5472.CAN-20-0571. Epub 2020 Aug 28.PMID: 32859606
Prospective validation of a clinical prediction score for survival in patients with spinal metastases: the New England Spinal Metastasis Score.
Schoenfeld AJ, Ferrone ML, Schwab JH, Blucher JA, Barton LB, Tobert DG, Chi JH, Shin JH, Kang JD, Harris MB.Spine J. 2021 Jan;21(1):28-36. doi: 10.1016/j.spinee.2020.02.009. Epub 2020 Feb 19